Telomere length determinants in childhood
نویسندگان
چکیده
منابع مشابه
Proximate determinants of telomere length in sand lizards (Lacerta agilis).
Telomeres are repeat sequences of non-coding DNA that cap the ends of chromosomes and contribute to their stability and the genomic integrity of cells. In evolutionary ecology, the main research target regarding these genomic structures has been their role in ageing and as a potential index of age. However, research on humans shows that a number of traits contribute to among-individual differen...
متن کاملTelomere length and body temperature—independent determinants of mammalian longevity?
WHY DO SPECIES DIFFER IN LIFESPAN AND WHAT ARE THE DETERMINANTS OF THEIR LONGEVITY? Understanding the main factors that determine variation in species longevity may provide a clue into the leading mechanisms of aging and—what is even more important—outline the key targets for longevity-promoting interventions. Comparative studies on longevity in mammals revealed numerous variables that correlat...
متن کاملChildhood Obesity Is Associated with Shorter Leukocyte Telomere Length
CONTEXT Obesity in adults is associated with shorter mean leukocyte telomere length (LTL), a marker of biological age that is also associated with age-related conditions including cardiovascular disease and type 2 diabetes. However, studies of childhood obesity and LTL have proved inconclusive. OBJECTIVE The objective of the study was to clarify the relationship between telomere length and ch...
متن کاملChildhood adversity, social support, and telomere length among perinatal women.
Adverse perinatal health outcomes are heightened among women with psychosocial risk factors, including childhood adversity and a lack of social support. Biological aging could be one pathway by which such outcomes occur. However, data examining links between psychosocial factors and indicators of biological aging among perinatal women are limited. The current study examined the associations of ...
متن کاملNo Correlation Between Childhood Maltreatment and Telomere Length
Telomeres are lengths of repetitive DNA that cap the ends of chromosomes. They protect the ends of the chromosome and shorten with each cell division. Short leukocyte telomere length has been related to a number of age-related diseases (1). In addition, shorter telomere length has been associated with environmental factors such as smoking and lack of exercise (2,3). In a recent issue of Biologi...
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine (CCLM)
سال: 2019
ISSN: 1437-4331,1434-6621
DOI: 10.1515/cclm-2019-0235